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[Use of tramadol versus pethidine versus denaverine suppositories in labor--a contribution to noninvasive therapy of labor pain].

Abstract
Because tramadol does not exhibit an depressive effect on ventilatory activity it is often be used in the obstetrical analgesia, at most in form of an intramuscularly injection. In a prospective study on at all 49 women under labour the clinical effect of the noninvasive rectal application of Tramadol, Pethidin, and Denaverin has been compared. The first dosage was 100 mg of all substances. Around the half of the women said that analgetic effect was good or very good. On only every fifth it was sufficient or not enough. The effect was at near the same in all treatment groups. Because of a low incidence of maternal side effects, the absence of side effects on the newborn, and near the same results on the analgetic effect of parenteral application in other studies, tramadol suppositories can be recommended for obstetrical analgesia.
AuthorsV Bredow
JournalZentralblatt fur Gynakologie (Zentralbl Gynakol) Vol. 114 Issue 11 Pg. 551-4 ( 1992) ISSN: 0044-4197 [Print] Germany
Vernacular TitleDie Anwendung von Tramadol- versus Pethidin- versus Denaverin-suppositorien unter der Geburt--ein Beitrag zur nichtinvasiven Geburtsschmerztherapie.
PMID1481587 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Benzilates
  • Parasympatholytics
  • Suppositories
  • Tramadol
  • Meperidine
  • denaverine
Topics
  • Analgesia, Obstetrical
  • Apgar Score
  • Benzilates (administration & dosage)
  • Female
  • Humans
  • Infant, Newborn
  • Meperidine (administration & dosage, adverse effects)
  • Pain Measurement
  • Parasympatholytics (administration & dosage, adverse effects)
  • Pregnancy
  • Suppositories
  • Tramadol (administration & dosage, adverse effects)

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