[Immune reactivity disorders in poisoning by the pyrethroid sumi-alpha].

Abstract

After subchronic intoxication with synthetic sumi-alpha pirethroid rats developed pronounced changes of macrophagocytic function; reduction of cell-mediated and humoral immunity, accumulation of pathogenic circulating immune complexes. In these conditions one-week thymalin treatment produced a normalizing effect. Sodium nucleinate was of low efficacy.

• Authors: S N Kuz'minskiĭ, V I Popko
• Journal: Likars'ka sprava (Lik Sprava) Issue 9 Pg. 88-90 (Sep 1992) ISSN: 1019-5297 [Print] Ukraine
• Vernacular Title: Narusheniia immunnoĭ reaktivnosti pri intoksikatsii piretroidom sumi-al'fa.
• PMID: 1481518 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Nitriles
• Nucleic Acids
• Pyrethrins
• Thymus Hormones
• thymalin
• sodium nucleinate
• fenvalerate

Topics

• Adjuvants, Immunologic (therapeutic use)
• Animals
• Antibody Formation (drug effects)
• Drug Evaluation, Preclinical
• Immune System Diseases (chemically induced, drug therapy)
• Immunity, Cellular (drug effects)
• Nitriles
• Nucleic Acids (therapeutic use)
• Poisoning (drug therapy, immunology)
• Pyrethrins (poisoning)
• Rats
• Rats, Wistar
• Thymus Hormones (therapeutic use)
• Time Factors