Abstract | BACKGROUND/AIMS: METHODS: RESULTS: CONCLUSIONS: The significant deterioration of neuropsychological test scores following induced hyperammonemia during the inflammatory state, but not after its resolution, suggests that the inflammation and its mediators may be important in modulating the cerebral effect of ammonia in liver disease.
|
Authors | Debbie L Shawcross, Nathan A Davies, Roger Williams, Rajiv Jalan |
Journal | Journal of hepatology
(J Hepatol)
Vol. 40
Issue 2
Pg. 247-54
(Feb 2004)
ISSN: 0168-8278 [Print] Netherlands |
PMID | 14739095
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
- Amino Acids
- Inflammation Mediators
- Ammonia
- C-Reactive Protein
|
Topics |
- Amino Acids
(blood)
- Ammonia
(blood)
- C-Reactive Protein
(metabolism)
- Female
- Hepatic Encephalopathy
(complications, immunology, psychology)
- Humans
- Hyperammonemia
(complications, immunology, psychology)
- Inflammation
(complications, immunology, psychology)
- Inflammation Mediators
(metabolism)
- Liver Cirrhosis
(complications, immunology, psychology)
- Male
- Mental Recall
- Middle Aged
- Neuropsychological Tests
- Reaction Time
|