Abstract |
A 33-year-old primipara with von Willebrand disease type I was admitted in labor at 37 weeks, requesting epidural analgesia. The consultant hematologist advised treating with desmopressin acetate ( DDAVP) before inserting an epidural catheter. Desmopressin at a dose of 0.3 microgram/Kg was administered intravenously and the catheter was inserted to L3-L4 to infuse 0.1% bupivacaine with 2 micrograms/mL of fentanyl at a rate of 12 mL/h. Four hours later the patient was brought to the operating room for forceps delivery of a healthy boy. One hour later, she had recovered normal motor tone followed by normal sensitivity in the lower extremities. The catheter was then withdrawn with no signs of bleeding. A woman with von Willebrand's disease can receive an epidural block for analgesia during childbirth. The decision to perform the block should be individualized, based on coagulation tests. DDAVP may play a role in improving hemostasis.
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Authors | P Pérez-Barrero, L Gil, C Martínez, A B Bueno, A I Casado, J Oro |
Journal | Revista espanola de anestesiologia y reanimacion
(Rev Esp Anestesiol Reanim)
Vol. 50
Issue 10
Pg. 526-9
(Dec 2003)
ISSN: 0034-9356 [Print] Spain |
Vernacular Title | Tratamiento con desmopresina (DDAVP) previo a la analgesia epidural del parto a una paciente con enfermedad de von Willebrand tipo I. |
PMID | 14737779
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
- Hemostatics
- Deamino Arginine Vasopressin
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Topics |
- Adult
- Analgesia, Epidural
- Analgesia, Obstetrical
- Deamino Arginine Vasopressin
(therapeutic use)
- Female
- Hemostatics
(therapeutic use)
- Humans
- Pregnancy
- Pregnancy Complications, Cardiovascular
(drug therapy)
- von Willebrand Diseases
(drug therapy)
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