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Role of proton magnetic resonance spectroscopy in the diagnosis of gliomatosis cerebri: a unique pattern of normal choline but elevated Myo-inositol metabolite levels.

Abstract
A patient with histologically proven gliomatosis cerebri presented with a normal choline level but a markedly abnormal elevated myo-inositol level on magnetic resonance (MR) spectroscopy. We describe the case presentation, imaging findings (in particular, the unique MR spectroscopic pattern), and their significance regarding the diagnosis of this relatively rare neoplasm.
AuthorsAurea V R Mohana-Borges, Steven G Imbesi, Rosalind Dietrich, John Alksne, Darius K Amjadi
JournalJournal of computer assisted tomography (J Comput Assist Tomogr) 2004 Jan-Feb Vol. 28 Issue 1 Pg. 103-5 ISSN: 0363-8715 [Print] United States
PMID14716242 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Inositol
  • Choline
Topics
  • Aged
  • Brain Neoplasms (chemistry, diagnosis, pathology)
  • Choline (analysis)
  • Humans
  • Inositol (analysis)
  • Magnetic Resonance Imaging
  • Magnetic Resonance Spectroscopy
  • Male
  • Neoplasms, Neuroepithelial (chemistry, diagnosis, pathology)

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