[Use of instenon in complex treatment of patients with optic nerve atrophy caused by craniocerebral trauma].

Abstract

Instenon, a combined nootropic agent, was used on the step-type basis within a complex treatment of optic nerve atrophy caused by craniocerebral trauma. Our study revealed that instenon, when used within a complex treatment of a partial optic nerve atrophy caused by craniocerebral trauma, improved the visual acuity in 85.7% of patients and it expanded the total visual field in 76.2% of patients, whereas the routine therapy ensured the related improvements in 58.9% and 61.5% of patients, respectively. Besides, the drug provided for a better retinal electric sensitivity and for a better optic nerve conduction in 73.8% of cases versus 64.1% of cases with basic therapy. Increased velocity parameters in the ocular-artery blood flow were registered in 77.1%, of patients who received instenon, by duplex scanning.

• Authors: M T Aznabaev, V A Khalikov, A Sh Zagidullina
• Journal: Vestnik oftalmologii (Vestn Oftalmol) 2003 Nov-Dec Vol. 119 Issue 6 Pg. 12-4 ISSN: 0042-465X [Print] Russia (Federation)
• Vernacular Title: Primenenie instenona v kompleksnom lechenii patsientov s atrofieĭ zritel'nogo nerva vsledstvie cherepno-mozgovoĭ travmy.
• PMID: 14708165 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Benzamides
• Drug Combinations
• Nootropic Agents
• Parasympathomimetics
• Vinca Alkaloids
• Neostigmine
• vinpocetine
• Instenon
• Hexobendine
• Theophylline

Topics

• Adolescent
• Adult
• Benzamides (administration & dosage, therapeutic use)
• Blood Flow Velocity
• Craniocerebral Trauma (complications)
• Drug Combinations
• Female
• Follow-Up Studies
• Hexobendine (administration & dosage, therapeutic use)
• Humans
• Male
• Middle Aged
• Neostigmine (administration & dosage, therapeutic use)
• Nootropic Agents (administration & dosage, therapeutic use)
• Ophthalmic Artery (diagnostic imaging, physiology)
• Optic Atrophy (drug therapy, etiology, therapy)
• Optic Nerve (physiology)
• Parasympathomimetics (administration & dosage, therapeutic use)
• Retina (physiology)
• Theophylline (administration & dosage, analogs & derivatives, therapeutic use)
• Time Factors
• Ultrasonography, Doppler, Duplex
• Vinca Alkaloids (administration & dosage, therapeutic use)
• Visual Acuity
• Visual Fields