Necrobiotic xanthogranuloma in a human T-lymphotropic virus type 1 carrier.

Abstract

A 67-year-old man who had necrobiotic xanthogranuloma associated with paraproteinemia is described. He was a human T-lymphotropic virus type 1 (HTLV-1) carrier who had a high titer of circulating anti-HTLV-1 antibodies and neurologic abnormalities that suggested HTLV-1-associated myelopathy. The patient's necrobiotic xanthogranuloma and neurologic symptoms improved after he received four 5-day courses of melphalan, 2 mg/day, and prednisolone, 20 mg/day, at 4-week intervals.

• Authors: M Nishimura, Y Takano-Nishimura, I Yano, N Hayashi, S Toshitani
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 27 Issue 5 Pt 2 Pg. 886-9 (Nov 1992) ISSN: 0190-9622 [Print] United States
• PMID: 1469152 (Publication Type: Case Reports, Journal Article)

Chemical References

• HTLV-I Antibodies

Topics

• Aged
• Granuloma (immunology, pathology)
• HTLV-I Antibodies (analysis)
• HTLV-I Infections (immunology, pathology)
• Humans
• Male
• Necrobiotic Disorders (immunology, pathology)
• Paraproteinemias
• Xanthomatosis (immunology, pathology)