Abstract |
Lewis acid activated donor-acceptor cyclopropanes react with aliphatic, aromatic, and alpha,beta-unsaturated nitriles in a novel cascade [3 + 2] dipolar cycloaddition, dehydration, and tautomerization sequence to afford pyrroles in moderate to excellent overall yield. This cost-effective and regiospecific method is ideally suited for the preparation of combinatorial libraries. [reaction: see text]
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Authors | Ming Yu, Brian L Pagenkopf |
Journal | Organic letters
(Org Lett)
Vol. 5
Issue 26
Pg. 5099-101
(Dec 25 2003)
ISSN: 1523-7060 [Print] United States |
PMID | 14682774
(Publication Type: Journal Article)
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