[Immunoglobulins in the treatment of herpes zoster].

Abstract

We have treated 20 patients with Herpes Zoster with "hyperimmune anti-Zoster immunoglobulins" (Uman-VZIG) by intralesional administration, 20 patients with Uman-VZIG by intramuscular administration and 23 patients with acyclovir by intravenous administration. The results of treatment in both groups of patients treated with Uman-VZIG were clinically satisfactory with disappearance of fever, local pain and amelioration of cutaneous lesions after two days from the start of treatment and with a mean duration of disease of five days. In patients treated with acyclovir, signs and symptomatology of disease ameliorated slowly and we have observed a longer mean duration of disease (about 8 days). We concluded that Uman-VZIG, both by intralesional and intramuscular administration, is effective and safe in Herpes Zoster treatment.

• Authors: G Agostini, S Agostini
• Journal: La Clinica terapeutica (Clin Ter) Vol. 141 Issue 9 Pt 2 Pg. 11-6 (Sep 1992) ISSN: 0009-9074 [Print] Italy
• Vernacular Title: Le immunoglobuline nel trattamento dell'herpes zoster.
• PMID: 1468193 (Publication Type: English Abstract, Journal Article)

Chemical References

• Acyclovir

Topics

• Acyclovir (therapeutic use)
• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Female
• Herpes Zoster (drug therapy, therapy)
• Humans
• Immunization, Passive (methods)
• Injections, Intralesional
• Injections, Intramuscular
• Male
• Middle Aged
• Treatment Outcome