[Influence of exercise on plasma concentration of neuropeptide Y in patients with essential hypertension].

Abstract

UNLABELLED:

Overactivity of sympathetic nervous system may lead to hypertension. The aim of this study was to assess changes of plasma concentration of neuropeptide Y in patients with hypertension after exercise.

MATERIAL AND METHODS:

The study group consisted of 46 patients with hypertension; the control group consisted of 29 healthy individuals. Plasma concentrations of neuropeptide Y, aldosterone, catecholamines and plasma renin activity were assessed before and after exercise performed on the treadmill.

RESULTS:

Plasma concentrations of aldosterone, catecholamines and plasma renin activity increased in both groups but plasma concentration of neuropeptide Y increased only in the hypertensive group (52.4 +/- 100.2 pg/ml vs 103.4 +/- 206.7 pg/ml, p < 0.05) but not in controls (51 +/- 36.3 pg/ml vs 70.8 +/- 134.9 pg/ml, p = NS).

CONCLUSION:

The increase of plasma concentration of neuropeptide Y after exercise in hypertensive group, but not in controls, indicates sympathetic nervous system overactivity in the study group.

• Authors: Dorota Zyśko
• Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego (Pol Merkur Lekarski) Vol. 15 Issue 87 Pg. 244-8 (Sep 2003) ISSN: 1426-9686 [Print] Poland
• Vernacular Title: Wpływ wysiłku fizycznego na osoczowe stezenie neuropeptydu Y u chorych na pierwotne nadciśnienie tetnicze.
• PMID: 14679849 (Publication Type: English Abstract, Journal Article)

Chemical References

• Catecholamines
• Neuropeptide Y
• Aldosterone
• Renin

Topics

• Aldosterone (blood)
• Catecholamines (blood)
• Exercise
• Female
• Humans
• Hypertension (blood, diagnosis)
• Male
• Middle Aged
• Neuropeptide Y (blood)
• Renin (blood)
• Severity of Illness Index