[The dynamics of cytostatic factor production by inactivated resident peritoneal macrophages from Syrian hamsters].

Abstract

Results presented indicate that resident peritoneal macrophages (Mph) of intact, or tumor-bearing Syrian hamsters release cytostatic factor(s) (CSF) independently on the presence of serum in culture medium and the degree of Mph adherence. Dynamics of CSF secretion and accumulation depends on the number of Mph and duration of time of CSF production. It has been shown that at later time of Mph cultivation (24 hours) supernatants examined can stimulate proliferation of the target cells.

• Authors: L G Burdelia
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 114 Issue 8 Pg. 189-91 (Jul 1992) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Dinamika produktsii tsitostaticheskogo faktora neaktivirovannymi rezidentnymi peritoneal'nymi makrofagami siriĭskikh khomiakov.
• PMID: 1467490 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Culture Media, Serum-Free
• Proto-Oncogene Proteins c-mos

Topics

• Animals
• Cell Adhesion (immunology)
• Cricetinae
• Culture Media, Serum-Free
• Cytotoxicity Tests, Immunologic (methods)
• Macrophage Activation (immunology)
• Macrophages (immunology)
• Mesocricetus
• Neoplasm Transplantation
• Neoplasms, Experimental (immunology)
• Peritoneal Cavity (cytology)
• Proto-Oncogene Proteins c-mos (metabolism)