Abstract | PROBLEM: METHOD OF STUDY: RESULTS: SIL-2R and, in particular, IL-12 was detected with significantly higher levels in missed abortion group compared with all other groups. IL-8 was detected with no significant difference among all the groups studied. CONCLUSIONS: In spite of caution due to the small sizes of the subject samples, these results support a role of the immune system in the first trimester pregnancy and hypothesize that missed abortion may be associated with an enhanced Th1 reactivity, whereas threatened abortion with good outcome resembles the normal pregnancy with a non-enhanced Th1 reactivity.
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Authors | Roberto Paradisi, Eleonora Porcu, Stefano Venturoli, Mario Maldini-Casadei, Paola Boni |
Journal | American journal of reproductive immunology (New York, N.Y. : 1989)
(Am J Reprod Immunol)
Vol. 50
Issue 4
Pg. 302-8
(Oct 2003)
ISSN: 1046-7408 [Print] Denmark |
PMID | 14672332
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Cytokines
- Inflammation Mediators
- Interleukin-8
- Receptors, Interleukin-2
- Interleukin-12
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Topics |
- Abortion, Missed
(blood, immunology)
- Abortion, Threatened
(blood, immunology)
- Adult
- Case-Control Studies
- Cytokines
(blood)
- Female
- Humans
- Inflammation Mediators
(blood)
- Interleukin-12
(blood)
- Interleukin-8
(blood)
- Leukocyte Count
- Pregnancy
- Receptors, Interleukin-2
(blood)
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