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[Treatment of laryngeal granuloma with anti-extraesophageal reflux medication].

AbstractOBJECTIVE:
To asses the role of Gastroesophageal reflux in the genesis of laryngeal granulomas.
PATIENTS AND METHODS:
Prospective series of 7 patients diagnosed of posterior laryngeal granuloma, 5 were male, and 2 female, ages ranging between 46 and 65 years, (only three with symptoms of gastroesophageal reflux), who followed an antireflux protocol (recommendations, omeprazol 20 mg, cisapride 20 mg, almagato 4000 mg daily).
RESULTS:
All cases did well, showing complete healing of the larynx 60 days after the beginning of treatment.
CONCLUSIONS:
Gastroesophageal reflux is an important factor in the genesis of posterior laryngeal granulomas. It seems appropriate to start an antireflux regimen before surgery, which can be chosen for non responders or cases with severe respiratory symptoms, hoarseness, or for definitive diagnosis.
AuthorsJ P Benaixa, F Esteban, J M González-Pérez, R Martínez-Garrido
JournalActa otorrinolaringologica espanola (Acta Otorrinolaringol Esp) 2003 Aug-Sep Vol. 54 Issue 7 Pg. 501-5 ISSN: 0001-6519 [Print] Spain
Vernacular TitleTratamiento de los granulomas de laringe con medicación anti-reflujo extraesofágico.
PMID14671922 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Antacids
  • Anti-Ulcer Agents
  • Carbonates
  • almagate
  • Aluminum Hydroxide
  • Omeprazole
  • Magnesium Hydroxide
  • Cisapride
Topics
  • Aged
  • Aluminum Hydroxide
  • Antacids
  • Anti-Ulcer Agents
  • Carbonates
  • Cisapride
  • Female
  • Gastroesophageal Reflux (drug therapy)
  • Granuloma, Respiratory Tract (drug therapy)
  • Humans
  • Laryngeal Diseases (drug therapy)
  • Magnesium Hydroxide
  • Male
  • Middle Aged
  • Omeprazole
  • Prospective Studies

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