Morphological study of reparative processes in the gingiva during therapy of chronic periodontitis with energostim and application of orthopedic splinting constructions.

Abstract

We studied morphological characteristics of the regenerative process in gingival tissues during therapy of chronic periodontitis. Energostim stimulated macrophageal reaction and promoted neoangiogenesis in the inflammatory infiltrate. It was not observed after traditional drug therapy. Energostim promoted vascularization in regenerating tissues, normalized the structure at a greater area of the lamina propria of the gingiva, and prevented fibrous and sclerotic changes. The volume of histiolymphocytic infiltrates in regenerating gingival tissues decreased after application of intradental splints.

• Authors: L A Faustov, V L Popkov, P A Galenko-Yaroshevskii, N L Sycheva, V N Meladze
• Journal: Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 136 Issue 3 Pg. 296-301 (Sep 2003) ISSN: 0007-4888 [Print] United States
• PMID: 14666199 (Publication Type: Journal Article)

Chemical References

• Drug Combinations
• energostim
• NAD
• Inosine
• Cytochromes c

Topics

• Capillaries (metabolism)
• Chronic Disease
• Cytochromes c (pharmacology)
• Drug Combinations
• Epithelium (metabolism)
• Fibroblasts (metabolism)
• Gingiva (blood supply, pathology)
• Gingivitis (pathology)
• Humans
• Inflammation
• Inosine (pharmacology)
• Macrophages (metabolism, pathology)
• Mucous Membrane (pathology)
• NAD (pharmacology)
• Periodontitis (drug therapy, metabolism)
• Splints
• Time Factors
• Wound Healing