HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Type 1 gastric carcinoid tumor: another extrahepatic manifestation of hepatitis C virus infection?

Abstract
A 67 year-old female with a 10-year history of cirrhosis due to hepatitis C virus who developed a gastric carcinoid tumor of the corpus is described. Carcinoid tumor was identified during her last routine gastroscopic evaluation for portal hypertension. In the case, serum parietal cell antibodies, hypergastrinemia and atrophic gastritis were also found. Chronic hepatitis C virus infection is known to induce clinical and laboratory signs of autoimmunity. But the question of whether hepatitis C virus plays a pathogenic role in the development of gastric carcinoid tumor is unknown. As far as we know, this is the first report describing gastric carcinoid tumor in hepatitis C virus induced chronic liver disease. We suggest that the possibility of the development of autoimmune atrophic gastritis and carcinoid tumors should be considered in patients with chronic hepatitis C that coexists with autoimmune diseases and has positive parietal cell antibodies.
AuthorsEser Vardareli, Tülay Sariçam, Serap Işiksoy, Hasan Yavuz, Ayşegül Ozakyol, Baybora Kircali
JournalThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology (Turk J Gastroenterol) Vol. 14 Issue 3 Pg. 194-6 (Sep 2003) ISSN: 1300-4948 [Print] Turkey
PMID14655065 (Publication Type: Case Reports, Journal Article)
Topics
  • Aged
  • Biopsy, Needle
  • Carcinoid Tumor (pathology, surgery)
  • Female
  • Follow-Up Studies
  • Gastrectomy (methods)
  • Gastritis, Atrophic (pathology)
  • Hepacivirus (isolation & purification)
  • Hepatitis C, Chronic (pathology)
  • Humans
  • Immunohistochemistry
  • Precancerous Conditions (pathology)
  • Risk Assessment
  • Stomach Neoplasms (pathology, surgery)
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: