[Influential factors to therapeutic efficacy of uterine artery embolization in the treatment of uterine fibroids].

Abstract

OBJECTIVE:

To investigate the therapeutic efficacy of uterine artery embolization in the treatment of uterine fibroids and to analyse the influential factors to the therapeutic efficacy.

METHODS:

Thirty-two patients with symptomatic uterine myomas were treated by superselective catheterization and embolization of bilateral uterine arteries using PVA particles. Patients were followed for 6 months after uterine artery embolization. Baseline symptoms and the volume of the fibroids were used as parameters to evaluate the therapeutic efficacy. Influential factors to therapeutic efficacy were analyzed.

RESULTS:

The clinical symptoms, especially heavy menstrual bleeding, were improved markedly. An average of 55.6% volume reduction of the fibroids was achieved during the 6 month follow-up. The submucosal and intramural location of the myomas reduced more in the volume compared with that of the subserosal location.

CONCLUSION:

Selective uterine artery embolization is effective for uterine myoma. Influential factors to the therapeutic efficacy may include: postprocedural vascular reconstruction in the fibroid, location of the fibroid, hemodynamic status of the fibroid, and the mode of embolization (unilateral or bilateral).

• Authors: Shun-ke Zhou, Shao-bo Li, Zi-shu Zhang
• Journal: Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University (Hunan Yi Ke Da Xue Xue Bao) Vol. 28 Issue 4 Pg. 409-11 (Aug 2003) ISSN: 1000-5625 [Print] China
• PMID: 14653133 (Publication Type: English Abstract, Journal Article)

Chemical References

• Polyvinyl Alcohol

Topics

• Adult
• Arteries
• Embolization, Therapeutic (methods)
• Female
• Follow-Up Studies
• Humans
• Leiomyoma (therapy)
• Middle Aged
• Polyvinyl Alcohol (therapeutic use)
• Treatment Outcome
• Uterine Neoplasms (therapy)
• Uterus (blood supply)