[The study on specific anti-Streptococcus mutans IgY against dental caries in rats].

Abstract

OBJECTIVE:

To investigate the effect of specific anti-streptococcus mutans IgY against streptococcus mutans on dental caries development in rats.

METHODS:

35 wistar rats were divided into 5 groups: group A received IgY gargle; group B received IgY lyophilized powder; group C received sterilized water as control; group D and E received egg yolk food with or without specific IgY individually. They were all fed with caries-inducing diet 2000#. The number of caries scores was counted by the procedure of Keyes'.

RESULTS:

There was a significant lower mean of caries scores in groups treated with IgY lyophilized powder and gargle. By treating with egg-yolk food contained specific IgY, the mean of caries scores decreased comparing with no treatment group.

CONCLUSION:

Local passive immunization with specific anti-streptococcus mutans IgY may be an effective way to prevent the development of dental caries.

• Authors: Mingwen Fan, Qianzhou Jiang, Zhuan Bian
• Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology (Hua Xi Kou Qiang Yi Xue Za Zhi) Vol. 21 Issue 5 Pg. 339-41 (Oct 2003) ISSN: 1000-1182 [Print] China
• PMID: 14650981 (Publication Type: English Abstract, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Bacterial
• IgY
• Immunoglobulins
• Streptococcal Vaccines

Topics

• Animals
• Antibodies, Bacterial (administration & dosage)
• Dental Caries (prevention & control)
• Female
• Immunization, Passive
• Immunoglobulins (immunology)
• Male
• Rats
• Rats, Wistar
• Streptococcal Vaccines (immunology)
• Streptococcus mutans (immunology)