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Possible mechanisms underlying the effect of natural preparations on erythropoiesis under conditions of conflict situation.

Abstract
We studied the effects of various natural preparations, including extracts of Siberian ginseng, Rhodiola rosea, bergenia, and ginseng and pantohematogen on erythropoiesis under conditions of conflict situation. The test preparations were divided into 2 groups depending on their modulatory effect on intensified erythropoiesis under conditions of conflict situation. Some of them reduced (extracts of ginseng, bergenia, and Rhodiola rosea), while others increased the degree of hyperplasia in the erythropoietic stem (extract of Siberian ginseng and pantohematogen). The regulatory effect of preparations depended on activity of the corresponding neurotransmitter systems in the brain and local regulatory mechanisms of hemopoiesis.
AuthorsN V Provalova, E G Skurikhin, O V Pershina, M Yu Minakova, N I Suslov, A M Dygai
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 136 Issue 2 Pg. 165-9 (Aug 2003) ISSN: 0007-4888 [Print] United States
PMID14631500 (Publication Type: Journal Article)
Chemical References
  • Biological Factors
  • Plant Extracts
  • pantohematogen
Topics
  • Animals
  • Biological Factors (chemistry, pharmacology)
  • Conflict, Psychological
  • Erythropoiesis (drug effects)
  • Mice
  • Mice, Inbred CBA
  • Panax (chemistry)
  • Plant Extracts (chemistry, pharmacology)
  • Plants, Medicinal (chemistry)
  • Rhodiola (chemistry)
  • Stem Cells (cytology, physiology)

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