[3 cases of sedation and analgesia using propofol and remifentanil for labor].

Abstract

Three women in labor for whom epidural analgesia was contraindicated--2 with sepsis (pylonephritis and chorioamnionitis) and 1 with sacral agenesia--were provided intravenous analgesia with propofol (0.4-1.2 mg/kg/h) and remifentanil (0.033-0.1 microgram/kg/min plus boluses of 20 micrograms controlled by the patient) with oxygen supplementation. Heart rate, noninvasive blood pressure, maternal oxygen saturation and fetal heart rate were monitored. Maternal satisfaction, quality of analgesia, maternal side effects (sedation, depression, breathing, muscle rigidity, nausea, and vomiting) and fetal side effects (heart rate variability and Apgar score) were evaluated. We conclude that in cases where epidural analgesia is contraindicated, intravenous perfusion of low doses of propofol and remifentanil can provide a valid alternative for analgesia during labor.

• Authors: F E Fontao Rodríguez
• Journal: Revista espanola de anestesiologia y reanimacion (Rev Esp Anestesiol Reanim) Vol. 50 Issue 8 Pg. 418-22 (Oct 2003) ISSN: 0034-9356 [Print] Spain
• Vernacular Title: Tres casos de sedación y analgesia con propofol y remifentanilo para el trabajo de parto.
• PMID: 14601371 (Publication Type: Case Reports, Journal Article)

Chemical References

• Analgesics
• Hypnotics and Sedatives
• Piperidines
• Remifentanil
• Propofol

Topics

• Adult
• Analgesia, Epidural
• Analgesia, Obstetrical (methods)
• Analgesia, Patient-Controlled
• Analgesics (administration & dosage, therapeutic use)
• Apgar Score
• Contraindications
• Female
• Fetus (drug effects)
• Humans
• Hypnotics and Sedatives (administration & dosage, therapeutic use)
• Infant, Newborn
• Infusions, Intravenous
• Patient Satisfaction
• Piperidines (administration & dosage, therapeutic use)
• Pregnancy
• Pregnancy Complications
• Propofol (administration & dosage, therapeutic use)
• Remifentanil