HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Recurrent spontaneous early pregnancy loss and low dose aspirin.

Abstract
Miscarriage is the most common complication of pregnancy, occurring in 10-15% of pregnant women. Accurate figures on prevalence are not available but it has been estimated that 2-5% of women have 3 or more miscarriages. The lack of methodological rigour in controlled trials of treatment efficacy in women with recurrent miscarriage makes it difficult to estimate the efficacy of treatment for this condition. To date, there is no evidence of improved outcome with aspirin compared to placebo or no treatment. Furthermore, animal data and limited human data suggest that prenatal use of aspirin may be associated with increased bleeding tendency, congenital malformations and cognitive and behavioural defects in the offspring. Seen and considered the lack of efficacy of low-dose aspirin and the potential for harm to the female and her offspring, the practice of recommending aspirin to women with recurrent miscarriage should be discontinued.
AuthorsS Daya
JournalMinerva ginecologica (Minerva Ginecol) Vol. 55 Issue 5 Pg. 441-9 (Oct 2003) ISSN: 0026-4784 [Print] Italy
PMID14581886 (Publication Type: Journal Article, Review)
Chemical References
  • Aspirin
Topics
  • Abortion, Habitual (etiology, prevention & control)
  • Antiphospholipid Syndrome (complications)
  • Aspirin (administration & dosage, adverse effects)
  • Clinical Trials as Topic
  • Female
  • Humans
  • Placenta (physiology)
  • Risk Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: