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Fructose breath hydrogen test--is it really a harmless diagnostic procedure?

Abstract
Usage of hydrogen breath tests has become one of the standard procedures in diagnosing chronic unspecific abdominal pain. These tests are said to be of sufficient specificity and sensitivity, are easily done, non-invasive and are more often practiced in outpatients. A 13-year-old boy is reported with chronic unspecific abdominal pain and growth retardation and so far misdiagnosed hereditary fructose intolerance (HFI), who developed life-threatening adverse effects during the fructose breath hydrogen test. It is concluded that the possibility of HFI should be excluded first by a carefully explored dietary history before the fructose breath test is performed under medical supervision. If there is any suspicion of HFI, a molecular genetic analysis should be preferred.
AuthorsP Müller, C Meier, H J Böhme, T Richter
JournalDigestive diseases (Basel, Switzerland) (Dig Dis) Vol. 21 Issue 3 Pg. 276-8 ( 2003) ISSN: 0257-2753 [Print] Switzerland
PMID14571104 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright 2003 S. Karger AG, Basel
Chemical References
  • Fructose
Topics
  • Abdominal Pain (diagnosis, etiology)
  • Adolescent
  • Breath Tests
  • Diagnosis, Differential
  • Fructose (adverse effects, metabolism)
  • Fructose Intolerance (diagnosis, genetics)
  • Growth Disorders (etiology, genetics)
  • Humans
  • Male
  • Sensitivity and Specificity

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