Petrosal sinus sampling in the diagnosis of Cushing's syndrome: preliminary experience in University of Malaya Medical Centre.

Abstract

Differentiating between Cushing's disease of pituitary origin and ectopic ACTH syndrome of extra-pituitary origin remains a major challenge to the clinician because of limitations in the diagnostic accuracy of the high-dose dexamethasone suppression test. Routine use of inferior petrosal sinus sampling (IPSS) is therefore advocated by some authors for these patients. We present our preliminary experience of IPSS in 7 consecutive patients with Cushing's disease and discuss how the results impacted on the patients' management.

• Authors: R Norlisah, B J Abdullah, F L Hew, S P Chan
• Journal: The Medical journal of Malaysia (Med J Malaysia) Vol. 58 Issue 2 Pg. 180-6 (Jun 2003) ISSN: 0300-5283 [Print] Malaysia
• PMID: 14569737 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Adrenocorticotropic Hormone

Topics

• Academic Medical Centers
• Adrenocorticotropic Hormone (blood)
• Adult
• Cushing Syndrome (blood, diagnosis, therapy)
• Female
• Humans
• Malaysia
• Male
• Middle Aged
• Petrosal Sinus Sampling
• Reproducibility of Results