[Effect of natural enterosorbents in experimental liver disorders].

Abstract

The effect of enterosorbents of natural origin, zoosterol and sodium alginate, on the main types of metabolism and the macro- and microelement composition (calcium, magnesium, zinc, copper) of the renal tissues was studied in animals with experimental nephrocalcinosis. Increased complex-forming ability of zoosterol, related to a higher absorption activity of low-molecular-weight fragments of this enterosorbent, favors retention of large molecules in the form of calcium salts in the parenchyma. Sodium alginate favors the elimination of calcium compounds and compensates for calcification of the renal tissue, which allows this this enterosorbent to be used as a crystal-inhibiting complex-forming agent for correcting metabolic dysbalance in cases of nephrocalcinosis.

• Authors: T A Gvozdenko, V I Ian'kova
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) 2003 Jul-Aug Vol. 66 Issue 4 Pg. 60-2 ISSN: 0869-2092 [Print] Russia (Federation)
• Vernacular Title: Deĭstvie énterosorbentov prirodnogo proiskhozhdeniia pri éksperimental'noĭ patologii pochek.
• PMID: 14558357 (Publication Type: Journal Article)

Chemical References

• Alginates
• Chelating Agents
• Ergocalciferols
• Hexuronic Acids
• Polysaccharides
• zosterin
• Copper
• Glucuronic Acid
• Magnesium
• Zinc
• Calcium

Topics

• Alginates (pharmacology)
• Animals
• Calcium (metabolism)
• Chelating Agents (pharmacology)
• Copper (metabolism)
• Enterosorption
• Ergocalciferols
• Glucuronic Acid (pharmacology)
• Hexuronic Acids (pharmacology)
• Kidney (drug effects, metabolism, pathology)
• Magnesium (metabolism)
• Male
• Nephrocalcinosis (chemically induced, metabolism, pathology)
• Polysaccharides (pharmacology)
• Rats
• Rats, Wistar
• Zinc (metabolism)