[The effect of the conditions for connective tissue formation during posttraumatic skin regeneration in rats on the adhesive properties of the epidermal cells].

Abstract

A cicatrix formed in the process of posttraumatic skin regeneration is characterized by a higher cell adhesion power in the upper, and, especially, in the middle epidermis stratum. The cell adhesion power indices in these strata, and cell mitotic activity of basal epidermis stratum near the cicatrix depend on conditions of connective tissue formation in the wound defect. The effect of physiological solution and trypsin on the wound process results in a moderate rising of intercellular contact strength and in decreasing in the number of dividing basal stratum cells, while addition of ronidase solution results in a sharp rising of the corneous scale adhesion strength, and in establishing the straight correlation between this index and the speed of epidermocyte production.

• Authors: T V Ershova, P P Ivanishchuk
• Journal: Tsitologiia (Tsitologiia) Vol. 34 Issue 6 Pg. 101-6 ( 1992) ISSN: 0041-3771 [Print] Russia (Federation)
• Vernacular Title: Vliianie usloviĭ formirovaniia soedinitel'noĭ tkani v protsesse posttravmaticheskoĭ regeneratsii kozhi u krys na adgezivnye svoĭstva kletok épidermisa.
• PMID: 1455556 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Hexosaminidases
• ronidase
• Trypsin

Topics

• Animals
• Cell Adhesion (drug effects)
• Cicatrix (etiology, physiopathology)
• Connective Tissue (drug effects, physiology)
• Epidermal Cells
• Epidermis (drug effects)
• Hexosaminidases (pharmacology)
• Male
• Rats
• Skin (drug effects, injuries)
• Skin Physiological Phenomena
• Time Factors
• Trypsin (pharmacology)
• Wound Healing (drug effects, physiology)