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[Clinical evaluation of provitamin B5 drops and gel for postoperative treatment of corneal and conjuctival injuries].

AbstractPURPOSE:
Vitamins B group are important ingredients of coenzymes. Provitamin B5 dexpanthenol is necessary in the processes of reconstruction of epithelium, has regenerative and anti-inflammatory properties. Objective of the study was to determine how the wounds of cornea and/or conjunctiva heal upon the application of D-panthenol/the medicine has been developed in the Faculty of Pharmacy of the Medical University of Gdańsk/.
MATERIAL AND METHODS:
The activity of the medicine was tested in 40 eyes in the test group, a 40 eyes in the control group did not receive D-panthenol. The degree of the objective and subjective symptoms was assessed.
RESULTS:
The differences between the two groups commenced on the second day following the operation. Better effects were observed in patients receiving D-panthenol. Congestion and oedema of conjunctiva withdrew, the edges of wounds demonstrated smoothness and better adherence. Subjective feelings improved.
CONCLUSIONS:
1. Provitamin B5 contained in 5% drops and 5% gel of D-panthenol effectively accelerates the processes of healing the wounds of conjunctiva and cornea.
AuthorsKrystyna Raczyńska, Barbara Iwaszkiewicz-Bilikiewicz, Wiesława Stozkowska, Jadwiga Sadlak-Nowicka
JournalKlinika oczna (Klin Oczna) Vol. 105 Issue 3-4 Pg. 175-8 ( 2003) ISSN: 0023-2157 [Print] Poland
Vernacular TitleKliniczna ocena kropli i zelu z prowitamina B5 w leczeniu pooperacyjnych ran rogówki i spojówki.
PMID14552179 (Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)
Chemical References
  • Gels
  • Ophthalmic Solutions
  • Pantothenic Acid
  • dexpanthenol
Topics
  • Conjunctiva (injuries, surgery)
  • Cornea (surgery)
  • Corneal Injuries
  • Epithelium, Corneal
  • Eye Injuries (drug therapy, etiology)
  • Gels
  • Humans
  • Keratotomy, Radial (adverse effects)
  • Middle Aged
  • Ophthalmic Solutions
  • Pantothenic Acid (administration & dosage, analogs & derivatives)
  • Phacoemulsification (adverse effects)
  • Postoperative Care (methods)
  • Wound Healing (drug effects)

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