Abstract | PURPOSE:
Vitamins B group are important ingredients of coenzymes. Provitamin B5 dexpanthenol is necessary in the processes of reconstruction of epithelium, has regenerative and anti-inflammatory properties. Objective of the study was to determine how the wounds of cornea and/or conjunctiva heal upon the application of D-panthenol/the medicine has been developed in the Faculty of Pharmacy of the Medical University of Gdańsk/. MATERIAL AND METHODS: The activity of the medicine was tested in 40 eyes in the test group, a 40 eyes in the control group did not receive D-panthenol. The degree of the objective and subjective symptoms was assessed. RESULTS: The differences between the two groups commenced on the second day following the operation. Better effects were observed in patients receiving D-panthenol. Congestion and oedema of conjunctiva withdrew, the edges of wounds demonstrated smoothness and better adherence. Subjective feelings improved. CONCLUSIONS: 1. Provitamin B5 contained in 5% drops and 5% gel of D-panthenol effectively accelerates the processes of healing the wounds of conjunctiva and cornea.
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Authors | Krystyna Raczyńska, Barbara Iwaszkiewicz-Bilikiewicz, Wiesława Stozkowska, Jadwiga Sadlak-Nowicka |
Journal | Klinika oczna
(Klin Oczna)
Vol. 105
Issue 3-4
Pg. 175-8
( 2003)
ISSN: 0023-2157 [Print] Poland |
Vernacular Title | Kliniczna ocena kropli i zelu z prowitamina B5 w leczeniu pooperacyjnych ran rogówki i spojówki. |
PMID | 14552179
(Publication Type: Clinical Trial, Controlled Clinical Trial, English Abstract, Journal Article)
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Chemical References |
- Gels
- Ophthalmic Solutions
- Pantothenic Acid
- dexpanthenol
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Topics |
- Conjunctiva
(injuries, surgery)
- Cornea
(surgery)
- Corneal Injuries
- Epithelium, Corneal
- Eye Injuries
(drug therapy, etiology)
- Gels
- Humans
- Keratotomy, Radial
(adverse effects)
- Middle Aged
- Ophthalmic Solutions
- Pantothenic Acid
(administration & dosage, analogs & derivatives)
- Phacoemulsification
(adverse effects)
- Postoperative Care
(methods)
- Wound Healing
(drug effects)
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