[Problems of hemostasis and hermetic properties in liver resections with application of fibrin-collagen substance].

Abstract

Forty-seven patients with various diseases of the liver were treated from 1992 to 2002. Patients had undergone liver resections of different scope. In 20 patients (study group) wound covering "Tachokomb" was used for final hemostasis and high hermetic properties of wound surface. Conventional suturing of the vessels and bile ducts was performed in 27 patients of the control group. Reliable hemostasis of the hepatic stump after anatomic resection was achieved in all the patients of the study group. Application of wound covering decreased time of final hemostasis, severity of hemorrhage and blood transfusion during surgery. Biliary complications after surgery were seen more often. Application of combined glue composition failed to reduce significantly rate of biliary complications after surgery, their rate increased proportionally to extension of liver resection.

• Authors: A G Bunatian, Z S Zavenian, N N Bagmet, G A Shatverian, O G Skipenko
• Journal: Khirurgiia (Khirurgiia (Mosk)) Issue 9 Pg. 18-23 ( 2003) ISSN: 0023-1207 [Print] Russia (Federation)
• Vernacular Title: Problemy gemostaza i germetizma pri rezektsiiakh pecheni s ispol'zovaniem fibrin-kollagenovoĭ substantsii.
• PMID: 14533376 (Publication Type: English Abstract, Journal Article)

Chemical References

• Drug Combinations
• tachocomb
• Fibrinogen
• Aprotinin
• Thrombin

Topics

• Adolescent
• Adult
• Aged
• Aprotinin (therapeutic use)
• Drug Combinations
• Female
• Fibrinogen (therapeutic use)
• Hemostasis, Surgical
• Hepatectomy (adverse effects, methods)
• Humans
• Male
• Middle Aged
• Thrombin (therapeutic use)
• Treatment Outcome
• Wound Healing (drug effects)