Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL.

AuthorsI M Appel, J P V Pinheiro, M L den Boer, C Lanvers, N C M Reniers, J Boos, R Pieters
JournalLeukemia (Leukemia) Vol. 17 Issue 11 Pg. 2254-6 (Nov 2003) ISSN: 0887-6924 [Print] England
PMID14523472 (Publication Type: Letter)
Chemical References
  • Antineoplastic Agents
  • pegaspargase
  • Polyethylene Glycols
  • Asparagine
  • Asparaginase
  • Antineoplastic Agents (administration & dosage, therapeutic use)
  • Asparaginase (administration & dosage, pharmacokinetics, therapeutic use)
  • Asparagine (cerebrospinal fluid, deficiency)
  • Child
  • Humans
  • Injections, Intravenous
  • Metabolic Clearance Rate
  • Polyethylene Glycols (administration & dosage, pharmacokinetics, therapeutic use)
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma (cerebrospinal fluid, drug therapy)
  • Time Factors

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