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Usefulness of bone marrow transplantation in the Hurler syndrome.

Abstract
The Hurler syndrome, an autosomal recessive storage disease of childhood, leads to death within the first decade of life from progressive deposition of glycosaminoglycans within the myointima of the coronary arteries and airways. Cardiac ultrasound findings of patients with this syndrome >10 years after successful bone marrow transplantation are described.
AuthorsElizabeth A Braunlin, Nanci R Stauffer, Charles H Peters, John L Bass, James M Berry, John J Hopwood, William Krivit
JournalThe American journal of cardiology (Am J Cardiol) Vol. 92 Issue 7 Pg. 882-6 (Oct 01 2003) ISSN: 0002-9149 [Print] United States
PMID14516901 (Publication Type: Clinical Trial, Journal Article)
Topics
  • Adolescent
  • Bone Marrow Transplantation (adverse effects)
  • Cardiovascular Physiological Phenomena
  • Child
  • Female
  • Follow-Up Studies
  • Heart Diseases (diagnostic imaging, etiology)
  • Humans
  • Male
  • Mucopolysaccharidosis I (complications, physiopathology, therapy)
  • Outcome Assessment, Health Care
  • Time
  • Ultrasonography

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