Abstract | BACKGROUND: METHODS: We describe a case of indolent mastocytosis presenting as scarring alopecia. The scalp biopsy revealed a perifollicular and dermal inflammatory infiltrate composed predominantly of mast cells, which was confirmed by tryptase and Giemsa stains. RESULTS: CONCLUSIONS: This case suggests that the diagnosis of mastocytosis should be entertained in patients presenting with scarring alopecia accompanied by an intense mast cell infiltrate on scalp biopsy and also supports the notion that mast cells may be involved in the pathogenesis of alopecia.
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Authors | Xiaowei Xu, Benjamin Solky, Rosalie Elenitsas, George Cotsarelis |
Journal | Journal of cutaneous pathology
(J Cutan Pathol)
Vol. 30
Issue 9
Pg. 561-5
(Oct 2003)
ISSN: 0303-6987 [Print] United States |
PMID | 14507404
(Publication Type: Case Reports, Journal Article)
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Topics |
- Alopecia
(etiology, pathology)
- Cicatrix
(pathology)
- Diagnosis, Differential
- Female
- Humans
- Mast Cells
(pathology)
- Mastocytosis, Cutaneous
(pathology)
- Middle Aged
- Scalp
(pathology)
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