| Abstract | A 14-year-old girl developed fever, severe headache, vomiting, and no light perception in both eyes over a 3-day period without a previous complaint of visual or other neurologic difficulties. Neuro-ophthalmologic examination was normal apart from meningismus and blindness. Brain imaging showed ventriculomegaly and multiple enhancing nodules around the optic chiasm. Lumbar puncture showed an elevated opening pressure with lymphocytic pleocytosis. Polymerase chain reaction and enzyme-linked immunoabsorbent antibody tests on the cerebrospinal fluid were positive for Mycobacterium tuberculosis. There was no evidence of tuberculosis elsewhere in the body. Standard antituberculous treatment, including corticosteroids, did not reverse the blindness. |
| Authors | Kumudini Sharma, Sunil Pradhan, Atul Varma, Bharti Rathi
(Affiliation: Department of Neurosurgery, Sanjay Gandhi Post-Graduate Institute of Medical Sciences, Lucknow (U.P.) 226014, India. kumud at sgpgi.ac.in)
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| Journal | Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
(J Neuroophthalmol)
Vol. 23
Issue 3
Pg. 211-2
(Sep 2003)
ISSN: 1070-8022 United States |
| PMID | 14504594
(Publication Type: Case Reports, Journal Article)
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| Chemical References |
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| Topics |
- Adolescent
- Antitubercular Agents
(therapeutic use)
- Blindness
(etiology)
- Cerebrospinal Fluid
(microbiology)
- Cisterna Magna
(pathology)
- Female
- Humans
- Magnetic Resonance Imaging
- Mycobacterium tuberculosis
(isolation & purification)
- Tuberculoma, Intracranial
(complications, diagnosis, drug therapy)
|
