[Treatment with ubiquinone in Kearns-Sayre syndrome. Improvement in ocular motility and visual evoked potentials].

Abstract

In 1985 Ogasahara observed that treatment with ubiquinone produced improvement in the cardiac conduction and the metabolism of the lactic and pyruvic acids in the Kearns-Sayre syndrome. The results of the administration of 150 mg/day of ubiquinone for 3 years in a patient diagnosed with the Kearns-Sayre syndrome is described. The patient improved notably in strength, ocular movement, visual evoked potentials and in the metabolism of lactic and pyruvic acids. Other beneficial effects reported in the literature have been improvement of ataxia and the somato-sensitive evoked potentials. No side effects have been described.

• Authors: M T Calatayud, A G Díaz-Castroverde, M Solar, M Díaz, D F Uría, C Martínez, C González, C Méndez
• Journal: Neurologia (Barcelona, Spain) (Neurologia) Vol. 7 Issue 9 Pg. 266-9 (Nov 1992) ISSN: 0213-4853 [Print] Spain
• Vernacular Title: Tratamiento con ubiquinona en el síndrome de Kearns-Sayre. Mejoría de la motilidad ocular y los potenciales evocados visuales.
• PMID: 1445712 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Ubiquinone

Topics

• Adolescent
• Electronystagmography
• Evoked Potentials, Visual
• Female
• Humans
• Kearns-Sayre Syndrome (drug therapy)
• Ubiquinone (therapeutic use)