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[Allergy to casein hydrolysate formula. A study of sensitizing allergen].

Abstract
A six-month old baby, who had been fed for 2 months with casein hydrolysate formula (MA-1) for treatment of milk allergy, developed diarrhea. The baby's RAST score for milk was negative. IgE antibodies to MA-1 but not to MA-1 depleted of lipid (fat-free MA-1), were demonstrated by enzyme-linked immunosorbent assay (ELISA). It was confirmed by the appearance of numerous mast cells and eosinophils in a rectal smear taken after challenge with MA-1 (but not detected after challenge with fat-free MA-1) that some component in the lipid of MA-1 must be an allergen in this patient.
AuthorsN Shimojo, N Shimizu, K Hirano, Y Kohno, H Niimi
JournalArerugi = [Allergy] (Arerugi) Vol. 41 Issue 9 Pg. 1413-8 (Sep 1992) ISSN: 0021-4884 [Print] Japan
PMID1444835 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Caseins
  • Immunoglobulin E
Topics
  • Caseins (immunology)
  • Colonic Diseases (immunology)
  • Enzyme-Linked Immunosorbent Assay
  • Humans
  • Immunoglobulin E (analysis)
  • Infant
  • Infant Food
  • Male
  • Milk Hypersensitivity (immunology)
  • Radioallergosorbent Test

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