[Ethonium in the treatment of peptic ulcer patients].

Abstract

Results are reported of clinical trials in 52 patients of ethonium belonging to quaternary ammonia compounds with consideration of the patients' age and concomitant disorders of the hepatobiliary system. It was established that ethonium possesses a marked antiradical and antioxidant effect in ulcer disease, furthering potentiation of the activity of peroxidedysmutase, protective enzymes of the glutathione system, improvement of bioenergetic processes in the gastric mucosa, enhancement of ulcer healing, prevention of ulcer recurrence.

• Authors: M Iu Kolomoets
• Journal: Likars'ka sprava (Lik Sprava) Issue 5 Pg. 65-9 (May 1992) ISSN: 1019-5297 [Print] Ukraine
• Vernacular Title: Etoniĭ v lechenii bol'nykh iazvennoĭ bolezn'iu.
• PMID: 1441415 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Anti-Ulcer Agents
• Antioxidants
• Quaternary Ammonium Compounds
• Ethonium

Topics

• Adult
• Aged
• Aged, 80 and over
• Anti-Ulcer Agents (therapeutic use)
• Antioxidants (therapeutic use)
• Chronic Disease
• Drug Evaluation
• Female
• Humans
• Male
• Middle Aged
• Peptic Ulcer (blood, drug therapy)
• Quaternary Ammonium Compounds (therapeutic use)