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6-Gingesulfonic acid, a new anti-ulcer principle, and gingerglycolipids A, B, and C, three new monoacyldigalactosylglycerols, from zingiberis rhizoma originating in Taiwan.

Abstract
By monitoring the effects on HCl/ethanol-induced gastric lesions in rats, a new antiulcer principle named 6-gingesulfonic acid was isolated from Zingiberis Rhizoma, the dried rhizome of Zingiber officinale Roscoe (cultivated and processed in Taiwan) together with three new monoacyldigalactosylglycerols named gingerglycolipids A, B and C. Their chemical structures were elucidated on the basis of chemical and physicochemical evidence. 6-Gingesulfonic acid showed more potent anti-ulcer activity than 6-gingerol and 6-shogaol.
AuthorsM Yoshikawa, S Hatakeyama, K Taniguchi, H Matuda, J Yamahara
JournalChemical & pharmaceutical bulletin (Chem Pharm Bull (Tokyo)) Vol. 40 Issue 8 Pg. 2239-41 (Aug 1992) ISSN: 0009-2363 [Print] Japan
PMID1423791 (Publication Type: Journal Article)
Chemical References
  • Anti-Ulcer Agents
  • Galactosides
  • Glycerides
  • Sulfonic Acids
  • 6-gingesulfonic acid
  • Guaiacol
Topics
  • Anti-Ulcer Agents (isolation & purification, pharmacology)
  • Galactosides (analysis, isolation & purification, pharmacology)
  • Glycerides (analysis, isolation & purification, pharmacology)
  • Guaiacol (analogs & derivatives, analysis, isolation & purification, pharmacology)
  • Plants, Medicinal (chemistry)
  • Sulfonic Acids (analysis, isolation & purification, pharmacology)
  • Taiwan

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