Abstract |
By monitoring the effects on HCl/ ethanol-induced gastric lesions in rats, a new antiulcer principle named 6-gingesulfonic acid was isolated from Zingiberis Rhizoma, the dried rhizome of Zingiber officinale Roscoe (cultivated and processed in Taiwan) together with three new monoacyldigalactosylglycerols named gingerglycolipids A, B and C. Their chemical structures were elucidated on the basis of chemical and physicochemical evidence. 6-Gingesulfonic acid showed more potent anti- ulcer activity than 6-gingerol and 6-shogaol.
|
Authors | M Yoshikawa, S Hatakeyama, K Taniguchi, H Matuda, J Yamahara |
Journal | Chemical & pharmaceutical bulletin
(Chem Pharm Bull (Tokyo))
Vol. 40
Issue 8
Pg. 2239-41
(Aug 1992)
ISSN: 0009-2363 [Print] Japan |
PMID | 1423791
(Publication Type: Journal Article)
|
Chemical References |
- Anti-Ulcer Agents
- Galactosides
- Glycerides
- Sulfonic Acids
- 6-gingesulfonic acid
- Guaiacol
|
Topics |
- Anti-Ulcer Agents
(isolation & purification, pharmacology)
- Galactosides
(analysis, isolation & purification, pharmacology)
- Glycerides
(analysis, isolation & purification, pharmacology)
- Guaiacol
(analogs & derivatives, analysis, isolation & purification, pharmacology)
- Plants, Medicinal
(chemistry)
- Sulfonic Acids
(analysis, isolation & purification, pharmacology)
- Taiwan
|