Ipsilateral cluster headache and chronic paroxysmal hemicrania: two case reports.

We report two patients with ipsilateral attacks of cluster headache and chronic paroxysmal hemicrania. The first patient, a 33-year-old man, started having attacks of chronic cluster headache at the age of 27. At 33, they were replaced by typical attacks of ipsilateral chronic paroxysmal hemicrania which showed a dramatic improvement with indomethacin 150 mg daily. After two days of complete remission, cluster headache attacks reappeared and persisted until verapamil, 360 mg a day, was added to indomethacin. The second patient, a 45-year-old man, first developed attacks of episodic cluster headache at the age of 35. At 44, he experienced ipsilateral typical attacks of chronic paroxysmal hemicrania, and two months later attacks of cluster headache. Under verapamil 240 mg daily, attacks of cluster headache disappeared, but those of chronic paroxysmal hemicrania increased in frequency until indomethacin 150 mg daily was added. These observations suggest a close relationship but not a similarity between cluster headache and chronic paraoxysmal hemicrania, and show the practical therapeutic interest of maintaining this distinction.
AuthorsA D Tehindrazanarivelo, J M Visy, M G Bousser
JournalCephalalgia : an international journal of headache (Cephalalgia) Vol. 12 Issue 5 Pg. 318-20 (Oct 1992) ISSN: 0333-1024 [Print] NORWAY
PMID1423564 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Verapamil
  • Indomethacin
  • Adult
  • Chronic Disease
  • Cluster Headache (complications)
  • Drug Therapy, Combination
  • Humans
  • Indomethacin (therapeutic use)
  • Male
  • Middle Aged
  • Migraine Disorders (complications)
  • Verapamil (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: