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Effect of cobra venom factor on experimental infection of mice against Clostridium chauvoei.

Abstract
The effect of cobra venom factor (CoVF) treatment was examined to clarify the mechanism of resistance of mice to Clostridium chauvoei infection. In CoVF-treated mice inoculated with spores of C. chauvoei, no death occurred and the organisms in the infected muscle progressively decreased, similar to that of non-treated control mice. These results indicated that C3 did not play a significant role in the resistance of mice against C. chauvoei infection.
AuthorsY Tamura, M Kijima, S Suzuki, T Takahashi, M Nakamura
JournalThe Journal of veterinary medical science (J Vet Med Sci) Vol. 54 Issue 5 Pg. 1049-50 (Oct 1992) ISSN: 0916-7250 [Print] Japan
PMID1420556 (Publication Type: Journal Article)
Chemical References
  • Complement C3
  • Elapid Venoms
  • cobra venom factor
Topics
  • Animals
  • Clostridium Infections (immunology, veterinary)
  • Complement C3 (drug effects, immunology)
  • Elapid Venoms (pharmacology)
  • Female
  • Immunity, Innate (drug effects)
  • Mice (immunology)

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