Successful treatment with pimozide of Capgras syndrome in an elderly male.

A case of Capgras syndrome in a 67-year-old man who failed to improve on haloperidol, but responded to pimozide, is described. The patient's paranoid delusions abated with 8 mg per day of pimozide. We believe pimozide's established benefit in the treatment of delusional disorders warrants its consideration in alleviating other delusions, including "the delusion of doubles."
AuthorsM J Tueth, J A Cheong
JournalJournal of geriatric psychiatry and neurology (J Geriatr Psychiatry Neurol) 1992 Oct-Dec Vol. 5 Issue 4 Pg. 217-9 ISSN: 0891-9887 [Print] UNITED STATES
PMID1418366 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Pimozide
  • Haloperidol
  • Capgras Syndrome (drug therapy, psychology)
  • Delusions (drug therapy, psychology)
  • Dose-Response Relationship, Drug
  • Haloperidol (therapeutic use)
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Paranoid Disorders (drug therapy, psychology)
  • Pimozide (therapeutic use)
  • Social Environment

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