Role of vitamin A and E in spondylosis.

Abstract

A biomedical study was undertaken at the Institute of Nutrition and Food Science, University of Dhaka to observe the effect of the antioxidative roles of vitamins A and E on the degenerative process occurring in spondylosis in human. A single and a double blind study were done. Thirty two patients suffering from spondylosis were selected for the study on the basis of certain criteria. The serum vitamin E level in most of the patients were lower (5.8 +/- 2.7 umol/L) than normal (11-41 umol/L). Vitamin E administration at a dose of 100 mg daily for three weeks resulted in a significant increase in serum vitamin E level accompanied by complete relief of pain. The serum vitamin A level of the patients were already within the normal (0.53-2 umol/L) range and vitamin A administration was not effective in relieving the pain. The results therefore strongly indicate that vitamin E is effective in curing spondylosis and most probably due to its antioxidant activity.

• Authors: Z Mahmud, S M Ali
• Journal: Bangladesh Medical Research Council bulletin (Bangladesh Med Res Counc Bull) Vol. 18 Issue 1 Pg. 47-59 (Apr 1992) ISSN: 0377-9238 [Print] Bangladesh
• PMID: 1417666 (Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Vitamin A
• Vitamin E

Topics

• Adult
• Aged
• Double-Blind Method
• Female
• Humans
• Male
• Middle Aged
• Single-Blind Method
• Spinal Osteophytosis (drug therapy)
• Vitamin A (therapeutic use)
• Vitamin E (therapeutic use)