HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

CLINICAL TRIALS WITH AGENTS CURRENTLY USED IN THE MANAGEMENT OF VAGINITIS.

Abstract
Results of treatment of 151 cases of vaginitis in patients attending a leukorrhea clinic were studied. The incidence of each type of vaginitis is recorded. Analysis of results of treatment with six compounds currently used in the therapy of vaginitis indicated that acetarsol or pimaricin compounds, with their broader spectra of activity, appeared to be most useful, prior to establishment of a definite diagnosis by means of cultures. Chlordantoin is an effective antifungal agent and is associated with a high percentage of "culture cures". Resistant cases should be investigated for diabetes mellitus, and many are aided by a low carbohydrate diet. Metronidazole was used only for resistant cases of trichomoniasis, with a cure rate of over 80% when both partners were treated simultaneously. Triple-sulfa vaginal cream was effective in over 80% of patients with nonspecific vaginitis; no cases of resistant bacterial infections were encountered. Dienestrol cream was effective in relieving the symptoms of atrophic vaginitis.
AuthorsJ R O'BRIEN
JournalCanadian Medical Association journal (Can Med Assoc J) Vol. 90 Pg. 1206-12 (May 23 1964) ISSN: 0008-4409 [Print] Canada
PMID14144540 (Publication Type: Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Antibiotics, Antitubercular
  • Antifungal Agents
  • Estrogens
  • Hydantoins
  • Imidazoles
  • Sulfonamides
  • Metronidazole
  • chlordantoin
  • Methazolamide
Topics
  • Anti-Bacterial Agents
  • Antibiotics, Antitubercular
  • Antifungal Agents
  • Atrophic Vaginitis
  • Bacterial Infections
  • Biomedical Research
  • Candidiasis, Vulvovaginal
  • Estrogens
  • Female
  • Humans
  • Hydantoins
  • Imidazoles
  • Intraabdominal Infections
  • Leukorrhea
  • Methazolamide
  • Metronidazole
  • Sulfonamides
  • Trichomonas Vaginitis
  • Vaginitis
  • Vaginosis, Bacterial
  • Vulvovaginitis

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: