[The role of the genotype in the development of suppurative inflammatory complications in trauma to the facial bones].

Abstract

The distribution of the genetic markers of leukocytes (HLA I and II), serum proteins (allotypes Gm, transferrin, haptoglobin, group-specific component), red cell enzymes (acid phosphatase--AP, phosphoglucomutase--PGM, esterase D, adenosine deaminase) was found to be universal in patients suffering from various pyoinflammatory diseases. The incidence of HLA A10, Cw4, DR5 antigens, IgG allotype G1m (2) and phenotype G1m (+1+2) and AP (aa) and PGM (2-2) phenotypes was found increased in patients with maxillofacial suppuration and pyoinflammatory complications of maxillofacial injuries as against normal subjects and patients with maxillofacial injuries without such complications. Traumatic osteomyelitis much more often develops in the carriers of the before genetic markers than in those in whom these markers are absent (61.6 and 20.4%, respectively).

• Authors: L A Grigor'iants, V P Zuev, L E Pospelov, E I Pushkina, T V Malinina, V I Litvinov
• Journal: Stomatologiia (Stomatologiia (Mosk)) 1992 Mar-Apr Issue 2 Pg. 40-2 ISSN: 0039-1735 [Print] Russia (Federation)
• Vernacular Title: Rol' genotipa v razvitii gnoĭno-vospalitel'nykh oslozhneniĭ pri travme litsevykh kosteĭ.
• PMID: 1412541 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Genetic Markers
• HLA Antigens

Topics

• Abscess (blood, epidemiology, etiology, genetics)
• Cellulitis (blood, epidemiology, etiology, genetics)
• Chi-Square Distribution
• Facial Bones (injuries)
• Focal Infection, Dental (blood, epidemiology, etiology, genetics)
• Genetic Markers
• Genotype
• HLA Antigens (blood, genetics)
• Humans
• Maxillofacial Injuries (blood, complications, epidemiology, genetics)
• Osteomyelitis (blood, epidemiology, etiology, genetics)
• Risk