Protection of rats against adjuvant arthritis by bacterial lipoplysaccharides.

Abstract	Lipopolysaccharides from both gram-negative and gram-positive bacteria in incomplete adjuvant caused rats to become resistant to mycobacterial (complete) adjuvant arthritis. Lipopolysaccharides h protected rats when they were administered in adjuvant did not protect when administered in saline. Mycobacterial wax D in saline was protective, while in adjuvant it produced arthritis. The degree of stimulation of a common tissue reaction may determine whether the result is protection or disease.
Authors	F D WOOD, C M PEARSON
Journal	Science (New York, N.Y.) (Science) Vol. 137 Issue 3529 Pg. 544-5 (Aug 17 1962) ISSN: 0036-8075 [Print] United States
PMID	14008167 (Publication Type: Journal Article)
Chemical References	Lipopolysaccharides
Topics	Animals Arthritis Arthritis, Experimental Bacteria (chemistry) Gram-Positive Bacteria Lipopolysaccharides (pharmacology) Rats

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