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Adrenal- and ovarian-vein steroids and LH response to GnRH in two patients with virilizing adrenocortical adenoma studied by selective catheterizations.

Abstract
Two women with androgen-secreting adrenal adenomas were studied by selective adrenal- and ovarian-vein catheterization. Blood samples were collected for determination of testosterone, androstenedione, dehydroepiandrosterone sulfate and cortisol. In a preoperative stimulation test with gonadotropin-releasing hormone, the response of luteinizing hormone was enhanced in both subjects. In catheterization studies, the venous gradients for the hormones were not diagnostic for the source of hyperandrogenism in either of the patients.
AuthorsK Ruutiainen, K Satokari, L Anttila, R Erkkola
JournalHormone research (Horm Res) Vol. 37 Issue 1-2 Pg. 49-53 ( 1992) ISSN: 0301-0163 [Print] Switzerland
PMID1398477 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Androgens
  • Gonadotropin-Releasing Hormone
  • Testosterone
  • Dehydroepiandrosterone
  • Dehydroepiandrosterone Sulfate
  • Luteinizing Hormone
  • Androsterone
  • Hydrocortisone
Topics
  • Adenoma (blood, metabolism)
  • Adrenal Cortex Neoplasms (blood, metabolism)
  • Adrenal Glands (blood supply)
  • Adult
  • Androgens (metabolism)
  • Androsterone (blood)
  • Catheterization
  • Dehydroepiandrosterone (analogs & derivatives, blood)
  • Dehydroepiandrosterone Sulfate
  • Female
  • Gonadotropin-Releasing Hormone
  • Humans
  • Hydrocortisone (blood)
  • Luteinizing Hormone (blood)
  • Ovary (blood supply)
  • Testosterone (blood)
  • Veins

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