Interleukin-5 levels of pleural fluid and serum samples in a patient with PIE syndrome.

Abstract

An increased production of IL-5 was detected in the pleural fluid (7.2 ng/ml) and in the serum samples (53 pg/ml) of a patient with PIE syndrome. Following steroid therapy, pleural fluid disappeared, eosinophilia improved and serum IL-5 concentration became undetectable. These results suggested that eosinophilia in the PIE syndrome is a consequence of increased production of IL-5, especially in the lung.

• Authors: R Matsumoto, M Ando, H Kohrogi, S Araki, K Takatsu
• Journal: Chest (Chest) Vol. 102 Issue 4 Pg. 1296-7 (Oct 1992) ISSN: 0012-3692 [Print] United States
• PMID: 1395793 (Publication Type: Case Reports, Journal Article)

Chemical References

• Interleukin-5

Topics

• Adult
• Enzyme-Linked Immunosorbent Assay
• Exudates and Transudates (chemistry)
• Female
• Humans
• Interleukin-5 (analysis)
• Pleural Effusion (etiology, metabolism)
• Pulmonary Eosinophilia (blood, complications, metabolism)