[Laparoscopic treatment of tubal pregnancy using local administration of prostaglandin F2 alpha].

Abstract

The present study reports on new treatment of tubal pregnancies by laparoscope-guided intratubal injection of prostaglandin F2 alpha into the affected tube. In 9 cases treated with PG, the method proved to be successful in 89%, as indicated by reduction of human chorionic gonadotropin (hCG) serum values to less than 20 IU/l. Preoperative serum hCG levels were 137 to 2520 IU/l (mean 1170 IU/l). In 8 women the serum concentration of beta hCG decreased to less than 20 IU/l in a mean time of 12.3 days. One woman needed surgical intervention 8 days after treatment as she continued to have abdominal pain. Hysterosalpingography 3 to 6 months after treatment showed tubal patency on the side of the pregnancy in two of three women who were examined. It is concluded that local prostaglandin F2 alpha treatment is a suitable method for termination of some tubal pregnancies.

• Authors: P Ventruba, Z Cupr
• Journal: Ceskoslovenska gynekologie (Cesk Gynekol) Vol. 57 Issue 1 Pg. 28-32 (Feb 1992) ISSN: 0374-6852 [Print] Czech Republic
• Vernacular Title: Laparoskopická lécba tubární gravidity lokální aplikací prostaglandinu F2 alpha.
• PMID: 1385760 (Publication Type: English Abstract, Journal Article)

Chemical References

• Chorionic Gonadotropin
• Dinoprost

Topics

• Adult
• Chorionic Gonadotropin (blood)
• Dinoprost (administration & dosage)
• Female
• Humans
• Laparoscopy
• Pregnancy
• Pregnancy, Tubal (blood, therapy)