Simultaneously occurring alopecia areata and Hodgkin's lymphoma: complete remission of both diseases with MOPP/ABV chemotherapy.

Abstract

A 43-year-old man presented with simultaneously occurring alopecia areata and stage IIIB nodular sclerosing Hodgkin's disease. Systemic symptoms of Hodgkin's disease were present for 6 months, and rapidly developing patchy hair loss of the scalp was present for 2 weeks prior to presentation. The patient was treated with eight cycles of MOPP-ABV chemotherapy that resulted in complete remission of Hodgkin's-disease. Four months after the completion of chemotherapy, the patient had normal hair regrowth with no evidence of alopecia areata. Alopecia areata may be an autoimmune disease and may respond to chemotherapy.

• Authors: P D Chan, M A Berk, O Kucuk, S Singh
• Journal: Medical and pediatric oncology (Med Pediatr Oncol) Vol. 20 Issue 4 Pg. 345-8 ( 1992) ISSN: 0098-1532 [Print] United States
• PMID: 1376855 (Publication Type: Case Reports, Journal Article)

Chemical References

• Bleomycin
• Procarbazine
• Mechlorethamine
• Vincristine
• Vinblastine
• Doxorubicin
• Prednisone

Topics

• Adult
• Alopecia Areata (drug therapy, etiology)
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Autoimmune Diseases (complications, drug therapy)
• Bleomycin (administration & dosage)
• Doxorubicin (administration & dosage)
• Hodgkin Disease (complications, drug therapy, pathology)
• Humans
• Male
• Mechlorethamine (administration & dosage)
• Neoplasm Staging
• Prednisone (administration & dosage)
• Procarbazine (administration & dosage)
• Remission Induction
• Vinblastine (administration & dosage)
• Vincristine (administration & dosage)