Rupture of ectopic pregnancy following disappearance of serum beta subunit of hCG.

Abstract

The introduction of sensitive assays for the beta subunit of hCG (beta-hCG) and improved ultrasound technology for diagnosis and monitoring of ectopic pregnancy have changed the clinical approach to the management of ectopic pregnancy. Only a few reports have been published of patients with ectopic gestation and negative serum beta-hCG levels. None of these described rupture of ectopic pregnancy following the decline of beta-hCG levels to below 10 mIU/mL. We describe a case of ectopic pregnancy, managed expectantly, in which rupture and hemoperitoneum occurred after the decline of beta-hCG levels to below 10 mIU/mL.

• Authors: D Hochner-Celnikier, M Ron, R Goshen, D Zacut, G Amir, S Yagel
• Journal: Obstetrics and gynecology (Obstet Gynecol) Vol. 79 Issue 5 ( Pt 2) Pg. 826-7 (May 1992) ISSN: 0029-7844 [Print] United States
• PMID: 1373479 (Publication Type: Case Reports, Journal Article)

Chemical References

• Chorionic Gonadotropin
• Chorionic Gonadotropin, beta Subunit, Human
• Peptide Fragments

Topics

• Adult
• Chorionic Gonadotropin (blood)
• Chorionic Gonadotropin, beta Subunit, Human
• Female
• Hemoperitoneum (etiology)
• Humans
• Peptide Fragments (blood)
• Pregnancy
• Pregnancy, Tubal (blood, diagnosis)
• Rupture, Spontaneous