The effect of methylpentynol and methylpentynol carbamate on the perfused superior cervical ganglion of the cat.

Abstract	The action of methylpentynol and methylpentynol carbamate on the perfused superior cervical ganglion of the cat was analysed. Both drugs, in doses of 1 to 5 mg., depressed the output of acetylcholine. If the acetylcholine output was reduced by more than about 50%, transmission failed. Both drugs also reduced the response of the ganglion to injected acetylcholine. The carbamate, but not methylpentynol itself, had a transient stimulant action on the ganglion, unaccompanied by acetylcholine release.
Authors	E MARLEY, W D PATON
Journal	British journal of pharmacology and chemotherapy (Br J Pharmacol Chemother) Vol. 14 Issue 2 Pg. 303-6 (Jun 1959) ISSN: 0366-0826 [Print] England
PMID	13662591 (Publication Type: Journal Article)
Chemical References	Carbamates Hypnotics and Sedatives Pentanols methylpentynol Acetylcholine methylpentynol carbamate
Topics	Acetylcholine Animals Carbamates Cats Ganglia Ganglia, Autonomic (drug effects) Hypnotics and Sedatives (pharmacology) Pentanols Superior Cervical Ganglion

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