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Some pharmacological properties of murexine (urocanoylcholine).

Abstract
Murexine (urocanoylcholine, [2-beta-imidazol-4(5)-ylacryloyloxyethyl] trimethylammonium bromide) has been shown to possess ganglion stimulating and neuromuscular blocking actions in cat, dog and rat. The blockade has been shown to be of the depolarizing type both on the basis of the resemblance of the pharmacological properties of the substance to that of known depolarizing blocking agents, and also directly by recording the depolarization produced in the endplate region of the gracilis muscle of the rat.
AuthorsM J KEYL, V P WHITTAKER
JournalBritish journal of pharmacology and chemotherapy (Br J Pharmacol Chemother) Vol. 13 Issue 1 Pg. 103-6 (Mar 1958) ISSN: 0366-0826 [Print] England
PMID13523145 (Publication Type: Journal Article)
Chemical References
  • Bromides
  • Imidazoles
  • imidazole
  • murexine
  • Choline
Topics
  • Animals
  • Bromides
  • Cats
  • Choline (analogs & derivatives)
  • Dogs
  • Felis
  • Imidazoles
  • Rats

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