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Padma 28 modifies immunological functions in experimental atherosclerosis in rabbits.

Abstract
The effect of Padma 28 on selected parameters of humoral and cellular immune reactions in rabbits subjected to experimental atherosclerosis was studied. The drug significantly reduced the size of atherosclerotic plaques in the aorta and restored to a varying extent the immune functions studied. The possible mechanism by which Padma 28 may exert its anti-atherosclerotic action is discussed in the scope of the immunological theory of atherosclerosis.
AuthorsJ Giełdanowski, T Dutkiewicz, L Samochowiec, J Wójcicki
JournalArchivum immunologiae et therapiae experimentalis (Arch Immunol Ther Exp (Warsz)) Vol. 40 Issue 5-6 Pg. 291-5 ( 1992) ISSN: 0004-069X [Print] Switzerland
PMID1340184 (Publication Type: Journal Article)
Chemical References
  • Hemagglutinins
  • Plant Extracts
  • Precipitins
  • Padma 28
Topics
  • Animals
  • Antibody Formation (drug effects)
  • Arteriosclerosis (drug therapy, etiology, immunology)
  • Blood Bactericidal Activity (drug effects)
  • Diet, Atherogenic
  • Hemagglutinins (biosynthesis)
  • Lymphocyte Activation (drug effects)
  • Male
  • Phagocytosis (drug effects)
  • Plant Extracts (pharmacology)
  • Precipitins (biosynthesis)
  • Rabbits

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