Treatment of wounds inflicted by rabid animals.

Abstract

This paper describes a series of experiments in which guinea-pigs were inoculated intramuscularly with a strain of fixed-virus rabies, and their wounds treated, after intervals of varying duration, with different viricidal substances. The authors found that cauterization with fuming nitric acid gave no greater protection against the development of rabies than did irrigation with a 20% soap-solution; a cationic detergent, Zephiran, was found to be the treatment of choice for wounds artificially contaminated with rabies virus.

• Authors: H J SHAUGHNESSY, J ZICHIS
• Journal: Bulletin of the World Health Organization (Bull World Health Organ) Vol. 10 Issue 5 Pg. 805-13 ( 1954) ISSN: 0042-9686 [Print] Switzerland
• PMID: 13182603 (Publication Type: Journal Article)

Chemical References

• Ammonium Compounds
• Anti-Infective Agents, Local
• Quaternary Ammonium Compounds

Topics

• Ammonium Compounds
• Animals
• Anti-Infective Agents, Local
• Guinea Pigs
• Quaternary Ammonium Compounds (pharmacology)
• Rabies
• Rabies virus